9 Best Keloid Scar Removal Methods 2025

If you're dealing with keloid scars, you know how challenging they can be. These raised, thick scars don't just disappear on their own – and they can continue growing well beyond the original wound. But here's the good news: there are effective methods to help reduce their appearance and minimize discomfort.

The prevalence of keloids ranges from 0.09% to 16% according to different countries or regions, with an estimated 11 million sufferers worldwide. If you're among them, you're definitely not alone in this journey.

Understanding Keloid Scars

Before we dive into solutions, let's get clear on what we're dealing with. Keloids are raised scars that grow beyond the boundaries of the original wound – unlike regular scars that stay put. They are firm, rubbery lesions or shiny, fibrous nodules that can vary from pink to the color of the person's skin or red to dark brown, and are sometimes accompanied by severe itchiness, pain, and changes in texture.

Lesions may develop as early as 1 to 3 months or as late as one year after injury. Keloid scarring is common in young people between the ages of 10 and 20, and in the United States, keloid scars are seen 15 times more frequently in people of sub-Saharan African descent than in people of European descent.

The 9 Most Effective Keloid Scar Removal Methods

1. Silicone Scar Products (Nuvadermis Advanced Solutions)

Let's start with one of the most accessible and clinically-backed options. Research has shown silicone to be effective and produce 86% reduction in texture, 84% in color and 68% in height of scars.

Nuvadermis silicone scar products offer professional-grade results at home. These scar sheets help to improve skin's color and texture so you can feel confident with smoother skin, with 24 hour wear using soft, lightweight, and breathable sheets made with premium medical-grade silicone. They're specifically designed to visibly improve the appearance of new and old scars, including keloid, surgical, and C-section scars, delivering continuous 24-hour coverage to support healing, reduce discoloration, and smooth skin texture.

What makes this method special:

  • Silicone gel sheeting is the gold-standard and non-invasive approach for hypertrophic and keloid scars and has remained the first-line therapy stated by international clinical recommendations on scar management

  • Significant improvement in color, thickness, and elasticity for both hypertrophic scars and keloids

  • Can be used alongside other methods

  • Minimal side effects with only 11.2% of patients reporting side effects, most commonly itching or irritated skin

For optimal effectiveness, apply the silicone sheet for at least three months and for at least four hours a day, though many users see results after 2-3 months of regular use.

2. Corticosteroid Injections

This is often considered the gold standard for keloid care among medical professionals. Intralesional steroids are among the most common approaches, helping to reduce the appearance of the scar when delivered directly into the keloid tissue.

Important considerations:

  • Multiple sessions needed every 4-6 weeks

  • Keloids show a strong tendency to recur when surgically excised in the absence of adjuvant therapies

  • Best combined with other approaches like Nuvadermis silicone products for enhanced results

3. Pressure Methods and Compression

Pressure approaches are supported by evidence as first-line therapy alongside silicone products. These work by reducing blood flow to the scar area, which can help minimize regrowth.

To see results, you'll need to wear the pressure device 12-20 hours daily for several months. The combination of silicone gel sheeting and compression therapy has been shown to be more effective than using sheets alone.

4. Cryotherapy (Freezing)

Cryotherapy can be useful but should be reserved for smaller lesions. The process involves freeze-thaw cycles to reduce scar tissue formation.

Best for:

  • Smaller keloids

  • Acne-related scars

  • Those with lighter skin tones

Caution: May cause pigment changes in darker skin. Consider combining with Nuvadermis silicone products post-procedure for better results.

5. Laser Therapy

Laser therapy is among the most common approaches and can reduce height and fade color of keloids. They're often combined with other methods like corticosteroid injections.

Pulsed dye laser therapy effectively reduces redness and discoloration, even in older scars, making it particularly valuable for improving the cosmetic appearance of keloids.

6. Radiation Therapy

Radiotherapy is among established approaches, and for over 100 years, radiation has helped minimize keloid regrowth after other methods. Radiotherapy mitigates fibroblast activity and inhibits dysfunctional blood vessel formation.

This approach is typically reserved for:

  • Severe cases

  • Post-surgical prevention

  • When other methods have failed

7. Surgical Excision (With Adjuvant Therapy)

Here's something crucial to understand: keloids show a strong tendency to recur when they are surgically excised in the absence of adjuvant therapies. That's why all surgical options should be followed by corticosteroid injections, silicone sheeting, or combined approaches.

Doctors often recommend combining revision surgery with steroid injections and post-surgical Nuvadermis silicone sheets for best results.

8. Combination Approaches

The reality is that dermatologists often recommend multiple approaches for keloids. Multiple approaches exist although none are uniformly successful, which is why using two or more methods typically improves results. This might include:

  • Nuvadermis silicone products + steroid injections

  • Pressure devices + laser therapy

  • Surgery + radiation + silicone products

9. Novel and Emerging Methods

Novel approaches include chemotherapy, immunotherapy, and anti-inflammatory therapies. While these are still being researched, they offer hope for difficult cases that don't respond to conventional approaches.

What Works Best: The Evidence

Despite the fact that keloids are common throughout the world, their epidemiology has not been adequately investigated, but evidence supports silicone sheeting and pressure approaches as first-line options.

The beneficial effects of silicone gel sheeting on care and prevention of hypertrophic and keloid scars have been confirmed, and since most patients develop these scars within 3 months after surgery or injury, silicone gel sheeting therapy should be started in the early repair phase to achieve optimal results.

Making the Right Choice for Your Situation

Your best approach depends on several factors:

  • Size and location of your keloid

  • How long you've had it

  • Your skin type and medical history

  • Your lifestyle and ability to follow through with methods

For many people, starting with non-invasive options like Nuvadermis silicone scar products makes the most sense. These advanced scar care solutions are designed to visibly reduce scars and restore your confidence while supporting your skin's natural processes.

Taking Action: Your Next Steps

Keloids remain a therapeutic challenge, so it's important to work with clinicians familiar with various options. The sooner you start addressing keloids, the better your chances of success.

Consider beginning with clinically-backed at-home solutions like Nuvadermis advanced scar care products. These dermatologist-tested formulas help reduce the appearance of scars while providing effective, gentle care that supports your skin. Whether you choose Nuvadermis silicone scar sheets or silicone scar tape, consistent application is key to seeing results.

Don't let keloid scars hold you back. With the right approach and consistent care, you can significantly improve both the appearance and comfort of your skin using methods that work – starting with proven solutions you can use at home today.